Testosterone dose-effect matchmaking inside fit men

I finish one to alterations in dispersing testosterone levels, triggered from the GnRH agonist and you can testosterone government, is actually in the testosterone dosage- and you may attention-depending alterations in fat-free size, strength proportions, fuel and you can electricity, lbs size, hemoglobin, HDL cholesterol, and you can IGF-We levels, inside the compliance which have an individual linear dose-effect relationship

Testosterone develops muscle mass and you may electricity and regulates almost every other mental procedure, however, we do not discover if or not testosterone effects is dosage based and you can if serving criteria getting keeping certain androgen-established procedure was equivalent. To search for the results of rated dosage out-of testosterone into the human anatomy composition, muscle dimensions, energy, electricity, sexual and intellectual services, prostate-certain antigen (PSA), plasma lipids, hemoglobin, and you may insulin-such as for instance development basis We (IGF-I) accounts, 61 eugonadal people, 18–35 yr, had been randomized to at least one of five communities for monthly shots regarding a lengthy-pretending gonadotropin-establishing hormone (GnRH) agonist, in order to suppress endogenous testosterone secretion, and a week shots out-of twenty five, fifty, 125, three hundred, or 600 milligrams regarding testosterone enanthate having 20 wk. Continue Reading